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Genome editing in maize directed by CRISPR–Cas9 ribonucleoprotein complexes

Targeted DNA double-strand breaks have been shown to significantly increase the frequency and precision of genome editing. In the past two decades, several double-strand break technologies have been developed. CRISPR–Cas9 has quickly become the technology of choice for genome editing due to its simp...

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Detalles Bibliográficos
Autores principales: Svitashev, Sergei, Schwartz, Christine, Lenderts, Brian, Young, Joshua K., Mark Cigan, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116081/
https://www.ncbi.nlm.nih.gov/pubmed/27848933
http://dx.doi.org/10.1038/ncomms13274