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Dendritic NMDA spikes are necessary for timing-dependent associative LTP in CA3 pyramidal cells

The computational repertoire of neurons is enhanced by regenerative electrical signals initiated in dendrites. These events, referred to as dendritic spikes, can act as cell-intrinsic amplifiers of synaptic input. Among these signals, dendritic NMDA spikes are of interest in light of their correlati...

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Detalles Bibliográficos
Autores principales: Brandalise, Federico, Carta, Stefano, Helmchen, Fritjof, Lisman, John, Gerber, Urs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116082/
https://www.ncbi.nlm.nih.gov/pubmed/27848967
http://dx.doi.org/10.1038/ncomms13480