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Carbene footprinting accurately maps binding sites in protein–ligand and protein–protein interactions

Specific interactions between proteins and their binding partners are fundamental to life processes. The ability to detect protein complexes, and map their sites of binding, is crucial to understanding basic biology at the molecular level. Methods that employ sensitive analytical techniques such as...

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Detalles Bibliográficos
Autores principales: Manzi, Lucio, Barrow, Andrew S., Scott, Daniel, Layfield, Robert, Wright, Timothy G., Moses, John E., Oldham, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116083/
https://www.ncbi.nlm.nih.gov/pubmed/27848959
http://dx.doi.org/10.1038/ncomms13288