Interleukin 37 limits monosodium urate crystal-induced innate immune responses in human and murine models of gout

BACKGROUND: Interleukin (IL)-37 has emerged as a fundamental inhibitor of innate immunity. Acute gout is a self-limiting inflammatory response to monosodium urate (MSU) crystals. In the current study, we assessed the preventive and therapeutic effect of recombinant human IL-37 (rhIL-37) in human and...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Lei, Xue, Yu, Zhu, Yingfeng, Xuan, Dandan, Yang, Xue, Liang, Minrui, Wang, Juan, Zhu, Xiaoxia, Zhang, Jiong, Zou, Hejian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116141/
https://www.ncbi.nlm.nih.gov/pubmed/27863506
http://dx.doi.org/10.1186/s13075-016-1167-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116141/
https://www.ncbi.nlm.nih.gov/pubmed/27863506
http://dx.doi.org/10.1186/s13075-016-1167-y

Ejemplares similares