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Interleukin 37 limits monosodium urate crystal-induced innate immune responses in human and murine models of gout

BACKGROUND: Interleukin (IL)-37 has emerged as a fundamental inhibitor of innate immunity. Acute gout is a self-limiting inflammatory response to monosodium urate (MSU) crystals. In the current study, we assessed the preventive and therapeutic effect of recombinant human IL-37 (rhIL-37) in human and...

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Detalles Bibliográficos
Autores principales:	Liu, Lei, Xue, Yu, Zhu, Yingfeng, Xuan, Dandan, Yang, Xue, Liang, Minrui, Wang, Juan, Zhu, Xiaoxia, Zhang, Jiong, Zou, Hejian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116141/ https://www.ncbi.nlm.nih.gov/pubmed/27863506 http://dx.doi.org/10.1186/s13075-016-1167-y

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