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Analysis of complement biomarkers in systemic sclerosis indicates a distinct pattern in scleroderma renal crisis

BACKGROUND: The complement system has been implicated in pathogenesis of systemic sclerosis (SSc). The goal of the present study was to evaluate improved complement biomarkers in SSc. METHODS: The presence of C4d, reflecting activation of the classical/lectin pathways, C3bBbP corresponding to activa...

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Detalles Bibliográficos
Autores principales: Okrój, Marcin, Johansson, Martin, Saxne, Tore, Blom, Anna M., Hesselstrand, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116178/
https://www.ncbi.nlm.nih.gov/pubmed/27863511
http://dx.doi.org/10.1186/s13075-016-1168-x