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Heme oxygenase-1-transduced bone marrow mesenchymal stem cells in reducing acute rejection and improving small bowel transplantation outcomes in rats

BACKGROUND: We determined whether bone marrow mesenchymal stem cells (BMMSCs) transduced with heme oxygenase-1 (HO-1), a cytoprotective and immune-protective factor, could improve outcomes for small bowel transplantation (SBTx) in rats. METHODS: We performed heterotopic SBTx from Brown Norway rats t...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Song, Hong Li, Zhang, Wen, Wu, Ben Juan, Fu, Nan Nan, Dong, Chong, Shen, Zhong Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116370/
https://www.ncbi.nlm.nih.gov/pubmed/27866474
http://dx.doi.org/10.1186/s13287-016-0427-8