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Possible therapeutic role of IgE blockade in irritable bowel syndrome
Omalizumab is a humanized monoclonal antibody that binds to the high-affinity type-I IgE Fc receptors on mast cells (MCs) and basophils, inhibiting the IgE immune pathway. Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, and dysregulation of the immune system l...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116590/ https://www.ncbi.nlm.nih.gov/pubmed/27920467 http://dx.doi.org/10.3748/wjg.v22.i43.9451 |