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Possible therapeutic role of IgE blockade in irritable bowel syndrome

Omalizumab is a humanized monoclonal antibody that binds to the high-affinity type-I IgE Fc receptors on mast cells (MCs) and basophils, inhibiting the IgE immune pathway. Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, and dysregulation of the immune system l...

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Detalles Bibliográficos
Autores principales: Magen, Eli, Chikovani, Tinatin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116590/
https://www.ncbi.nlm.nih.gov/pubmed/27920467
http://dx.doi.org/10.3748/wjg.v22.i43.9451