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Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis
All cellular proteins are synthesized by ribosomes, whose biogenesis in eukaryotes is a complex multi-step process completed within minutes. Several chemical inhibitors of ribosome function are available and used as tools or drugs. By contrast, we lack potent validated chemical probes to analyze the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116814/ https://www.ncbi.nlm.nih.gov/pubmed/27667686 http://dx.doi.org/10.1016/j.cell.2016.08.070 |