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Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis

All cellular proteins are synthesized by ribosomes, whose biogenesis in eukaryotes is a complex multi-step process completed within minutes. Several chemical inhibitors of ribosome function are available and used as tools or drugs. By contrast, we lack potent validated chemical probes to analyze the...

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Detalles Bibliográficos
Autores principales:	Kawashima, Shigehiro A., Chen, Zhen, Aoi, Yuki, Patgiri, Anupam, Kobayashi, Yuki, Nurse, Paul, Kapoor, Tarun M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116814/ https://www.ncbi.nlm.nih.gov/pubmed/27667686 http://dx.doi.org/10.1016/j.cell.2016.08.070

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