Oncogenic mechanisms of HOXB13 missense mutations in prostate carcinogenesis

The recurrent germline mutation HOXB13 p.(Gly84Glu) (G84E) has recently been identified as a risk factor for prostate cancer. In a recent study, we have performed full sequencing of the HOXB13 gene in 462 Portuguese prostate cancer patients with early-onset and/or familial/hereditary disease, and id...

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Detalles Bibliográficos
Autores principales: Cardoso, Marta, Maia, Sofia, Paulo, Paula, Teixeira, Manuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116946/
https://www.ncbi.nlm.nih.gov/pubmed/28050579
http://dx.doi.org/10.18632/oncoscience.322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116946/
https://www.ncbi.nlm.nih.gov/pubmed/28050579
http://dx.doi.org/10.18632/oncoscience.322

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