IGFBP1 increases β‐cell regeneration by promoting α‐ to β‐cell transdifferentiation

There is great interest in therapeutically harnessing endogenous regenerative mechanisms to increase the number of β cells in people with diabetes. By performing whole‐genome expression profiling of zebrafish islets, we identified 11 secreted proteins that are upregulated during β‐cell regeneration....

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Detalles Bibliográficos
Autores principales: Lu, Jing, Liu, Ka‐Cheuk, Schulz, Nadja, Karampelias, Christos, Charbord, Jérémie, Hilding, Agneta, Rautio, Linn, Bertolino, Philippe, Östenson, Claes‐Göran, Brismar, Kerstin, Andersson, Olov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116948/
https://www.ncbi.nlm.nih.gov/pubmed/27516442
http://dx.doi.org/10.15252/embj.201592903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116948/
https://www.ncbi.nlm.nih.gov/pubmed/27516442
http://dx.doi.org/10.15252/embj.201592903

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