Notch signaling promotes nephrogenesis by downregulating Six2

During nephrogenesis, multipotent mesenchymal nephron progenitors develop into distinct epithelial segments. Each nephron segment has distinct cell types and physiological function. In the current model of kidney development, Notch signaling promotes the formation of proximal tubules and represses t...

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Detalles Bibliográficos
Autores principales: Chung, Eunah, Deacon, Patrick, Marable, Sierra, Shin, Juhyun, Park, Joo-Seop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117151/
https://www.ncbi.nlm.nih.gov/pubmed/27633993
http://dx.doi.org/10.1242/dev.143503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117151/
https://www.ncbi.nlm.nih.gov/pubmed/27633993
http://dx.doi.org/10.1242/dev.143503

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