PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position

Disruption of epithelial architecture is a fundamental event during epithelial tumorigenesis. We show that the expression of the cancer-promoting phosphatase PRL-3 (PTP4A3), which is overexpressed in several epithelial cancers, in polarized epithelial MDCK and Caco2 cells leads to invasion and the f...

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Detalles Bibliográficos
Autores principales: Luján, Pablo, Varsano, Giulia, Rubio, Teresa, Hennrich, Marco L., Sachsenheimer, Timo, Gálvez-Santisteban, Manuel, Martín-Belmonte, Fernando, Gavin, Anne-Claude, Brügger, Britta, Köhn, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117205/
https://www.ncbi.nlm.nih.gov/pubmed/27656108
http://dx.doi.org/10.1242/jcs.190215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117205/
https://www.ncbi.nlm.nih.gov/pubmed/27656108
http://dx.doi.org/10.1242/jcs.190215

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