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A reporter model to visualize imprinting stability at the Dlk1 locus during mouse development and in pluripotent cells
Genomic imprinting results in the monoallelic expression of genes that encode important regulators of growth and proliferation. Dysregulation of imprinted genes, such as those within the Dlk1-Dio3 locus, is associated with developmental syndromes and specific diseases. Our ability to interrogate cau...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117214/ https://www.ncbi.nlm.nih.gov/pubmed/27729406 http://dx.doi.org/10.1242/dev.138255 |