Garcinol Upregulates GABA(A) and GAD65 Expression, Modulates BDNF-TrkB Pathway to Reduce Seizures in Pentylenetetrazole (PTZ)-Induced Epilepsy

BACKGROUND: Epilepsy is the most predominant neurological disorder characterized by recurrent seizures. Despite treatment with antiepileptic drugs, epilepsy still is a challenge to treat, due to the associated adverse effects of the drugs. Previous investigations have shown critical roles of BDNF-Tr...

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Detalles Bibliográficos
Autores principales: Hao, Fang, Jia, Li-Hua, Li, Xiao-Wan, Zhang, Ying-Rui, Liu, Xue-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117238/
https://www.ncbi.nlm.nih.gov/pubmed/27855137
http://dx.doi.org/10.12659/MSM.897579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117238/
https://www.ncbi.nlm.nih.gov/pubmed/27855137
http://dx.doi.org/10.12659/MSM.897579

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