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Glycopyrrolate in comparison to hyoscine hydrobromide and placebo in the treatment of hypersalivation induced by clozapine (GOTHIC1): study protocol for a randomised controlled feasibility study

BACKGROUND: Clozapine is the only medication licensed for the treatment of resistant schizophrenia in the UK. Although efficacious, a common and unpopular side effect of clozapine treatment is clozapine-induced hypersalivation (CIH), which can contribute to non-adherence. The standard treatment for...

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Detalles Bibliográficos
Autores principales: Qurashi, Inti, Chu, Simon, Husain, Nusrat, Drake, Richard J., Chaudhry, Imran, Deakin, J. F. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117505/
https://www.ncbi.nlm.nih.gov/pubmed/27871302
http://dx.doi.org/10.1186/s13063-016-1678-5