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Most of the tight positional conservation of transcription factor binding sites near the transcription start site reflects their co-localization within regulatory modules

BACKGROUND: Transcription factors (TFs) form complexes that bind regulatory modules (RMs) within DNA, to control specific sets of genes. Some transcription factor binding sites (TFBSs) near the transcription start site (TSS) display tight positional preferences relative to the TSS. Furthermore, near...

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Detalles Bibliográficos
Autores principales: Acevedo-Luna, Natalia, Mariño-Ramírez, Leonardo, Halbert, Armand, Hansen, Ulla, Landsman, David, Spouge, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117513/
https://www.ncbi.nlm.nih.gov/pubmed/27871221
http://dx.doi.org/10.1186/s12859-016-1354-5