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Association of tryptophan hydroxylase-2 polymorphisms with oppositional defiant disorder in a Chinese Han population

BACKGROUND: Oppositional defiant disorder (ODD) is a behavioral disorder of school-age population. It is well known that 5-HT dysfunction is correlated with impulsivity, which is one of the common characteristics of ODD. The enzyme tryptophan hydroxylase-2 (TPH-2) synthesizes 5-HT in serotonergic ne...

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Detalles Bibliográficos
Autores principales: Wang, Chang-Hong, Liu, Cong, Cong, En-Zhao, Xu, Gai-Ling, Lv, Ting-Ting, Zhang, Ying-Li, Ning, Qiu-Fen, Wang, Ji-Kang, Nie, Hui-Yao, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117514/
https://www.ncbi.nlm.nih.gov/pubmed/27871272
http://dx.doi.org/10.1186/s12993-016-0113-0