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Tryptophan hydroxylase 1 and 5-HT(7) receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling

BACKGROUND: Triple-negative breast cancer (TNBC) has a high risk of relapse and there are few chemotherapy options. Although 5-hydroxytryptamine (5-HT, serotonin) signaling pathways have been suggested as potential targets for anti-cancer drug development, the mechanism responsible for the action of...

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Detalles Bibliográficos
Autores principales: Gautam, Jaya, Banskota, Suhrid, Regmi, Sushil Chandra, Ahn, Subi, Jeon, Yong Hyun, Jeong, Hyunyoung, Kim, Seung Joo, Nam, Tae-gyu, Jeong, Byeong-Seon, Kim, Jung-Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117586/
https://www.ncbi.nlm.nih.gov/pubmed/27871326
http://dx.doi.org/10.1186/s12943-016-0559-6