Synergistic Inhibition of Protein Fibrillation by Proline and Sorbitol: Biophysical Investigations

We report here interesting synergistic effects of proline and sorbitol, two well-known chemical chaperones, in the inhibition of fibrillation of two proteins, insulin and lysozyme. A combination of many biophysical techniques has been used to understand the structural morphology and modes of interac...

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Detalles Bibliográficos
Autores principales: Choudhary, Sinjan, Save, Shreyada N., Kishore, Nand, Hosur, Ramakrishna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117683/
https://www.ncbi.nlm.nih.gov/pubmed/27870861
http://dx.doi.org/10.1371/journal.pone.0166487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117683/
https://www.ncbi.nlm.nih.gov/pubmed/27870861
http://dx.doi.org/10.1371/journal.pone.0166487

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