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Synergistic Inhibition of Protein Fibrillation by Proline and Sorbitol: Biophysical Investigations
We report here interesting synergistic effects of proline and sorbitol, two well-known chemical chaperones, in the inhibition of fibrillation of two proteins, insulin and lysozyme. A combination of many biophysical techniques has been used to understand the structural morphology and modes of interac...
Autores principales: | Choudhary, Sinjan, Save, Shreyada N., Kishore, Nand, Hosur, Ramakrishna V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117683/ https://www.ncbi.nlm.nih.gov/pubmed/27870861 http://dx.doi.org/10.1371/journal.pone.0166487 |
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