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High expression of EPB41L5, an integral component of the Arf6-driven mesenchymal program, correlates with poor prognosis of squamous cell carcinoma of the tongue

BACKGROUND: Squamous cell carcinoma of the tongue (tongue SCC) is a major subtype of head and neck squamous cell carcinoma (HNSCC), which is an intractable cancer under current therapeutics. ARF6 and its effector AMAP1 are often overexpressed in different types of cancers, such as breast cancer and...

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Detalles Bibliográficos
Autores principales: Otsuka, Yutaro, Sato, Hiroki, Oikawa, Tsukasa, Onodera, Yasuhito, Nam, Jin-Min, Hashimoto, Ari, Fukunaga, Kiyoshi, Hatanaka, Kanako C., Hatanaka, Yutaka, Matsuno, Yoshihiro, Fukuda, Satoshi, Sabe, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117685/
https://www.ncbi.nlm.nih.gov/pubmed/27871329
http://dx.doi.org/10.1186/s12964-016-0151-0