Activin Receptor Type IIB Inhibition Improves Muscle Phenotype and Function in a Mouse Model of Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a devastating neurodegenerative disorder that causes progressive muscle atrophy and weakness. Using adeno-associated virus-mediated gene transfer, we evaluated the potential to improve skeletal muscle weakness via systemic, postnatal inhibition of either myostatin or...

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Detalles Bibliográficos
Autores principales: Liu, Min, Hammers, David W., Barton, Elisabeth R., Sweeney, H. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117715/
https://www.ncbi.nlm.nih.gov/pubmed/27870893
http://dx.doi.org/10.1371/journal.pone.0166803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117715/
https://www.ncbi.nlm.nih.gov/pubmed/27870893
http://dx.doi.org/10.1371/journal.pone.0166803

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