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All-trans retinoic acid shifts rosiglitazone-induced adipogenic differentiation to osteogenic differentiation in mouse embryonic fibroblasts

Rosiglitazone (RSG) is a potent drug used in the treatment of insulin resistance; however, it is associated with marked skeletal toxicity. RSG-induced osteoporosis may contribute to the promotion of adipogenic differentiation at the expense of osteogenic differentiation in bone marrow stromal cells....

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Detalles Bibliográficos
Autores principales: Shao, Ying, Chen, Qian-Zhao, Zeng, Yu-Hua, Li, Yang, Ren, Wen-Yan, Zhou, Lin-Yun, Liu, Rong-Xin, Wu, Ke, Yang, Jun-Qing, Deng, Zhong-Liang, Yu, Yu, Sun, Wen-Juan, He, Bai-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117762/
https://www.ncbi.nlm.nih.gov/pubmed/27779644
http://dx.doi.org/10.3892/ijmm.2016.2782