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M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus

Monoamine oxidases (MAO), downstream targets of glucocorticoid, maintain the turnover and homeostasis of monoamine neurotransmitters; yet, its pathophysiological role in monoamine deficiency, oxidative stress and neuroinflammation remains controversial. Protective effects of M30, a brain selective M...

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Detalles Bibliográficos
Autores principales: Lam, Chun-Sing, Tipoe, George Lim, Wong, Johnny Kong-Ching, Youdim, Moussa B. H., Fung, Man-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117770/
https://www.ncbi.nlm.nih.gov/pubmed/27870896
http://dx.doi.org/10.1371/journal.pone.0166966