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The complexity of integrins in cancer and new scopes for therapeutic targeting

Cancer is a complex disease and progresses within a dynamically evolving extracellular matrix that controls virtually every aspect of the tumour and tumour-associated cells. Interactions with the extracellular microenvironment are predominately mediated by a family of cell-surface transmembrane rece...

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Detalles Bibliográficos
Autores principales: Hamidi, Hellyeh, Pietilä, Mika, Ivaska, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117799/
https://www.ncbi.nlm.nih.gov/pubmed/27685444
http://dx.doi.org/10.1038/bjc.2016.312