Cargando…
Structural basis for precursor protein-directed ribosomal peptide macrocyclization
Macrocyclization is a common feature of natural product biosynthetic pathways including the diverse family of ribosomal peptides. Microviridins are architecturally complex cyanobacterial ribosomal peptides whose members target proteases with potent reversible inhibition. The product structure is con...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117808/ https://www.ncbi.nlm.nih.gov/pubmed/27669417 http://dx.doi.org/10.1038/nchembio.2200 |