Axl-EGFR receptor tyrosine kinase hetero-interaction provides EGFR with access to pro-invasive signalling in cancer cells

Acquired resistance to conventional and targeted therapies is becoming a major hindrance in cancer management. It is increasingly clear that cancer cells are able to evolve and rewire canonical signalling pathways to their advantage, thus evading cell death and promoting cell invasion. The Axl recep...

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Detalles Bibliográficos
Autores principales: Vouri, M, Croucher, D R, Kennedy, S P, An, Q, Pilkington, G J, Hafizi, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117851/
https://www.ncbi.nlm.nih.gov/pubmed/27775700
http://dx.doi.org/10.1038/oncsis.2016.66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117851/
https://www.ncbi.nlm.nih.gov/pubmed/27775700
http://dx.doi.org/10.1038/oncsis.2016.66

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