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Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators

Inflammatory pain is thought to arise from increased transmission from nociceptors and recruitment of 'silent' afferents. To evaluate inflammation-induced changes, mice expressing GCaMP3 in cutaneous sensory neurons were generated and neuronal responses to mechanical stimulation in vivo be...

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Detalles Bibliográficos
Autores principales: Smith-Edwards, Kristen M, DeBerry, Jennifer J, Saloman, Jami L, Davis, Brian M, Woodbury, C Jeffery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117853/
https://www.ncbi.nlm.nih.gov/pubmed/27805567
http://dx.doi.org/10.7554/eLife.20527