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Functional asymmetry and electron flow in the bovine respirasome

Respirasomes are macromolecular assemblies of the respiratory chain complexes I, III and IV in the inner mitochondrial membrane. We determined the structure of supercomplex I(1)III(2)IV(1) from bovine heart mitochondria by cryo-EM at 9 Å resolution. Most protein-protein contacts between complex I, I...

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Detalles Bibliográficos
Autores principales: Sousa, Joana S, Mills, Deryck J, Vonck, Janet, Kühlbrandt, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117854/
https://www.ncbi.nlm.nih.gov/pubmed/27830641
http://dx.doi.org/10.7554/eLife.21290