Oncolytic adenovirus expressing interleukin-18 improves antitumor activity of dacarbazine for malignant melanoma

Conditionally replicating adenoviruses have emerged as novel therapeutic agents for cancer. This study aimed to evaluate synergistic antitumor activity of replication-competent adenovirus armed with interleukin (IL)-18 (ZD55-IL-18) and dacarbazine (DTIC) against melanoma. Melanoma A375 cells or nude...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Chunhua, Cao, Hang, Liu, Ning, Xu, Kai, Ding, Meng, Mao, Li-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117872/
https://www.ncbi.nlm.nih.gov/pubmed/27895465
http://dx.doi.org/10.2147/DDDT.S115121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117872/
https://www.ncbi.nlm.nih.gov/pubmed/27895465
http://dx.doi.org/10.2147/DDDT.S115121

Ejemplares similares