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Oncolytic adenovirus expressing interleukin-18 improves antitumor activity of dacarbazine for malignant melanoma

Conditionally replicating adenoviruses have emerged as novel therapeutic agents for cancer. This study aimed to evaluate synergistic antitumor activity of replication-competent adenovirus armed with interleukin (IL)-18 (ZD55-IL-18) and dacarbazine (DTIC) against melanoma. Melanoma A375 cells or nude...

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Detalles Bibliográficos
Autores principales:	Yang, Chunhua, Cao, Hang, Liu, Ning, Xu, Kai, Ding, Meng, Mao, Li-jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117872/ https://www.ncbi.nlm.nih.gov/pubmed/27895465 http://dx.doi.org/10.2147/DDDT.S115121

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