Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis

Sildenafil is the first phosphodiesterase-5 inhibitor used for the treatment of erectile dysfunction. However, recent studies have been suggesting an antitumor effect of sildenafil. The current study assessed the aforementioned activity of sildenafil in vivo and in vitro in solid-tumor-bearing mice...

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Detalles Bibliográficos
Autores principales: El-Naa, Mona Mohamed, Othman, Mohamed, Younes, Sheren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117873/
https://www.ncbi.nlm.nih.gov/pubmed/27895461
http://dx.doi.org/10.2147/DDDT.S107490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117873/
https://www.ncbi.nlm.nih.gov/pubmed/27895461
http://dx.doi.org/10.2147/DDDT.S107490

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