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Increased localized delivery of piroxicam by cationic nanoparticles after intra-articular injection

Piroxicam (PRX), a potent nonsteroidal anti-inflammatory drug, is prescribed to relieve postoperative and/or chronic joint pain. However, its oral administration often results in serious gastrointestinal adverse effects including duodenal ulceration. Thus, a novel cationic nanoparticle (NP) was expl...

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Detalles Bibliográficos
Autores principales: Kim, Sung Rae, Ho, Myoung Jin, Kim, Sang Hyun, Cho, Ha Ra, Kim, Han Sol, Choi, Yong Seok, Choi, Young Wook, Kang, Myung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117887/
https://www.ncbi.nlm.nih.gov/pubmed/27895468
http://dx.doi.org/10.2147/DDDT.S118145