Noninvasive monitoring of early antiangiogenic therapy response in human nasopharyngeal carcinoma xenograft model using MRI with RGD-conjugated ultrasmall superparamagnetic iron oxide nanoparticles

PURPOSE: Arginine-glycine-aspartic acid (RGD)-based nanoprobes allow specific imaging of integrin αvβ3, a protein overexpressed during angiogenesis. Therefore, this study applied a novel RGD-coupled, polyacrylic acid (PAA)-coated ultrasmall superparamagnetic iron oxide (USPIO) (referred to as RGD-PA...

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Detalles Bibliográficos
Autores principales: Cui, Yanfen, Zhang, Caiyuan, Luo, Ran, Liu, Huanhuan, Zhang, Zhongyang, Xu, Tianyong, Zhang, Yong, Wang, Dengbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117895/
https://www.ncbi.nlm.nih.gov/pubmed/27895477
http://dx.doi.org/10.2147/IJN.S115357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117895/
https://www.ncbi.nlm.nih.gov/pubmed/27895477
http://dx.doi.org/10.2147/IJN.S115357

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