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Noninvasive monitoring of early antiangiogenic therapy response in human nasopharyngeal carcinoma xenograft model using MRI with RGD-conjugated ultrasmall superparamagnetic iron oxide nanoparticles

PURPOSE: Arginine-glycine-aspartic acid (RGD)-based nanoprobes allow specific imaging of integrin αvβ3, a protein overexpressed during angiogenesis. Therefore, this study applied a novel RGD-coupled, polyacrylic acid (PAA)-coated ultrasmall superparamagnetic iron oxide (USPIO) (referred to as RGD-PA...

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Detalles Bibliográficos
Autores principales:	Cui, Yanfen, Zhang, Caiyuan, Luo, Ran, Liu, Huanhuan, Zhang, Zhongyang, Xu, Tianyong, Zhang, Yong, Wang, Dengbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117895/ https://www.ncbi.nlm.nih.gov/pubmed/27895477 http://dx.doi.org/10.2147/IJN.S115357

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