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Lentivirus-mediated knockdown of NLK inhibits small-cell lung cancer growth and metastasis

Nemo-like kinase (NLK), an evolutionarily conserved serine/threonine kinase, has been recognized as a critical regulator of various cancers. In this study, we investigated the role of NLK in human small-cell lung cancer (SCLC), which is the most aggressive form of lung cancer. NLK expression was eva...

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Detalles Bibliográficos
Autores principales: Lv, Mutian, Li, Yaming, Tian, Xin, Dai, Shundong, Sun, Jing, Jin, Guojiang, Jiang, Shenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117896/
https://www.ncbi.nlm.nih.gov/pubmed/27895463
http://dx.doi.org/10.2147/DDDT.S87435