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Simvastatin Rapidly and Reversibly Inhibits Insulin Secretion in Intact Single-Islet Cultures

INTRODUCTION: Epidemiological studies suggest that statins may promote the development or exacerbation of diabetes, but whether this occurs through inhibition of insulin secretion is unclear. This lack of understanding is partly due to the cellular models used to explore this phenomenon (cell lines...

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Detalles Bibliográficos
Autores principales: Scattolini, Valentina, Luni, Camilla, Zambon, Alessandro, Galvanin, Silvia, Gagliano, Onelia, Ciubotaru, Catalin Dacian, Avogaro, Angelo, Mammano, Fabio, Elvassore, Nicola, Fadini, Gian Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118248/
https://www.ncbi.nlm.nih.gov/pubmed/27830474
http://dx.doi.org/10.1007/s13300-016-0210-y