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Structural Insights into Substrate Recognition by Clostridium difficile Sortase

Sortases function as cysteine transpeptidases that catalyze the covalent attachment of virulence-associated surface proteins into the cell wall peptidoglycan in Gram-positive bacteria. The substrate proteins targeted by sortase enzymes have a cell wall sorting signal (CWSS) located at the C-terminus...

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Detalles Bibliográficos
Autores principales: Yin, Jui-Chieh, Fei, Chun-Hsien, Lo, Yen-Chen, Hsiao, Yu-Yuan, Chang, Jyun-Cyuan, Nix, Jay C., Chang, Yuan-Yu, Yang, Lee-Wei, Huang, I-Hsiu, Wang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118464/
https://www.ncbi.nlm.nih.gov/pubmed/27921010
http://dx.doi.org/10.3389/fcimb.2016.00160