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Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway

The development of chemoresistance to cisplatin regimens causes a poor prognosis in patients with advanced NSCLC. The role of noncanonical Wnt signaling in the regulation of properties of lung cancer stem cells and chemoresistance was interrogated, by accessing capacities of cell proliferation, migr...

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Detalles Bibliográficos
Autores principales: Yang, Jiali, Zhang, Kangjian, Wu, Jing, Shi, Juan, Xue, Jing, Li, Jing, Chen, Juan, Zhu, Yongzhao, Wei, Jun, He, Jinxi, Liu, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118537/
https://www.ncbi.nlm.nih.gov/pubmed/27895670
http://dx.doi.org/10.1155/2016/1690896