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Cl-out is a novel cooperative optogenetic tool for extruding chloride from neurons

Chloride regulation affects brain function in many ways, for instance, by dictating the GABAergic reversal potential, and thereby influencing neuronal excitability and spike timing. Consistent with this, there is increasing evidence implicating chloride in a range of neurological conditions. Investi...

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Detalles Bibliográficos
Autores principales: Alfonsa, Hannah, Lakey, Jeremy H., Lightowlers, Robert N., Trevelyan, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118542/
https://www.ncbi.nlm.nih.gov/pubmed/27853135
http://dx.doi.org/10.1038/ncomms13495