Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice

Individuals with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D) induced by high calorie western diet are characterized by enhanced lipogenesis and gluconeogenesis in the liver. Stimulation of reductive amination may shift tricarboxylic acid cycle metabolism for lipogenesis and g...

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Detalles Bibliográficos
Autores principales: Han, Seung Jin, Choi, Sung-E, Yi, Sang-A, Jung, Jong Gab, Jung, Ik-Rak, Shin, Maureen, Kang, Seok, Oh, Hyunhee, Kim, Hae Jin, Kim, Dae Jung, Kwon, Ji Eun, Choi, Cheol Soo, Lee, Kwan Woo, Kang, Yup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118703/
https://www.ncbi.nlm.nih.gov/pubmed/27874078
http://dx.doi.org/10.1038/srep37468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118703/
https://www.ncbi.nlm.nih.gov/pubmed/27874078
http://dx.doi.org/10.1038/srep37468

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