Structural basis of TRPA1 inhibition by HC-030031 utilizing species-specific differences

Pain is a harmful sensation that arises from noxious stimuli. Transient receptor potential ankyrin 1 (TRPA1) is one target for studying pain mechanisms. TRPA1 is activated by various stimuli such as noxious cold, pungent natural products and environmental irritants. Since TRPA1 is an attractive targ...

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Detalles Bibliográficos
Autores principales: Gupta, Rupali, Saito, Shigeru, Mori, Yoshiharu, Itoh, Satoru G., Okumura, Hisashi, Tominaga, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118716/
https://www.ncbi.nlm.nih.gov/pubmed/27874100
http://dx.doi.org/10.1038/srep37460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118716/
https://www.ncbi.nlm.nih.gov/pubmed/27874100
http://dx.doi.org/10.1038/srep37460

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