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Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABA(A) Receptor Positive Allosteric Modulator
Rationale: Current first-line treatments for stress-related disorders such as major depressive disorder (MDD) act on monoaminergic systems and take weeks to achieve a therapeutic effect with poor response and low remission rates. Recent research has implicated the GABAergic system in the pathophysio...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118774/ https://www.ncbi.nlm.nih.gov/pubmed/27920723 http://dx.doi.org/10.3389/fphar.2016.00446 |