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Aloe-emodin suppresses hypoxia-induced retinal angiogenesis via inhibition of HIF-1α/VEGF pathway

Background: Aloe-emodin (AE) has been reported to possess the antiangiogenic effect on laser induced choroidal neovascularization. AE inhibits the vessel formation in the zebrafish embryos. However, it is still unclear whether AE can alleviate neovascularization. Here, we investigated the inhibitory...

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Detalles Bibliográficos
Autores principales: Wu, Jianming, Ke, Xiao, Wang, Wei, Zhang, Hongcheng, Ma, Na, Fu, Wei, Zhao, Manxi, Gao, Xiaoping, Hao, Xiaofeng, Zhang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118782/
https://www.ncbi.nlm.nih.gov/pubmed/27877088
http://dx.doi.org/10.7150/ijbs.16334