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Antimicrobial Peptide Potency is Facilitated by Greater Conformational Flexibility when Binding to Gram-negative Bacterial Inner Membranes
The interaction of antimicrobial peptides (AMPs) with the inner membrane of Gram-negative bacteria is a key determinant of their abilities to exert diverse bactericidal effects. Here we present a molecular level understanding of the initial target membrane interaction for two cationic α-helical AMPs...
Autores principales: | Amos, Sarah-Beth T. A., Vermeer, Louic S., Ferguson, Philip M., Kozlowska, Justyna, Davy, Matthew, Bui, Tam T., Drake, Alex F., Lorenz, Christian D., Mason, A. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118786/ https://www.ncbi.nlm.nih.gov/pubmed/27874065 http://dx.doi.org/10.1038/srep37639 |
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