Silymarin attenuates cigarette smoke extract-induced inflammation via simultaneous inhibition of autophagy and ERK/p38 MAPK pathway in human bronchial epithelial cells

Cigarette smoke (CS) is a major risk of chronic obstructive pulmonary disease (COPD), contributing to airway inflammation. Our previous study revealed that silymarin had an anti-inflammatory effect in CS-exposed mice. In this study, we attempt to further elucidate the molecular mechanisms of silymar...

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Detalles Bibliográficos
Autores principales: Li, Diandian, Hu, Jun, Wang, Tao, Zhang, Xue, Liu, Lian, Wang, Hao, Wu, Yanqiu, Xu, Dan, Wen, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118787/
https://www.ncbi.nlm.nih.gov/pubmed/27874084
http://dx.doi.org/10.1038/srep37751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118787/
https://www.ncbi.nlm.nih.gov/pubmed/27874084
http://dx.doi.org/10.1038/srep37751

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