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Silymarin attenuates cigarette smoke extract-induced inflammation via simultaneous inhibition of autophagy and ERK/p38 MAPK pathway in human bronchial epithelial cells
Cigarette smoke (CS) is a major risk of chronic obstructive pulmonary disease (COPD), contributing to airway inflammation. Our previous study revealed that silymarin had an anti-inflammatory effect in CS-exposed mice. In this study, we attempt to further elucidate the molecular mechanisms of silymar...
Autores principales: | Li, Diandian, Hu, Jun, Wang, Tao, Zhang, Xue, Liu, Lian, Wang, Hao, Wu, Yanqiu, Xu, Dan, Wen, Fuqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118787/ https://www.ncbi.nlm.nih.gov/pubmed/27874084 http://dx.doi.org/10.1038/srep37751 |
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