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Complex lasso: new entangled motifs in proteins

We identify new entangled motifs in proteins that we call complex lassos. Lassos arise in proteins with disulfide bridges (or in proteins with amide linkages), when termini of a protein backbone pierce through an auxiliary surface of minimal area, spanned on a covalent loop. We find that as much as...

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Detalles Bibliográficos
Autores principales: Niemyska, Wanda, Dabrowski-Tumanski, Pawel, Kadlof, Michal, Haglund, Ellinor, Sułkowski, Piotr, Sulkowska, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118788/
https://www.ncbi.nlm.nih.gov/pubmed/27874096
http://dx.doi.org/10.1038/srep36895